Which Aromatase Inhibitor Is Best With Least Side Effects

Premenopausal women who also get ovarian suppression.

Which aromatase inhibitor is best with least side effects.

Joint and muscle pain. The most common side effects of ais are symptoms of menopause such as hot flashes night sweats and vaginal dryness. Aromatase inhibitors are used in the treatment of breast cancer to reduce levels of circulating estrogen. The side effects of all three drugs are similar.

Side effects of anastrozole and letrozole that are similar include nausea vomiting and headache. The brand name for anastrozole is arimidex and the brand name for letrozole is femara both drugs are available in generic form. Which aromatase inhibitor causes the fewest side effects. People often ask if one drug causes fewer side effects than the others.

Joint pain arthralgia and muscle pain myalgia are common side effects of aromatase inhibitors. Anastrozole and letrozole are both aromatase inhibitors anti cancer medications used for treating postmenopausal women with breast cancer. Aromatase inhibitors and risk reduction. These drugs can also cause muscle and joint pain.

Nausea and vomiting diarrhea and constipation hot flashes headache bone pain severe fatigue skin rash swelling and water retention. These drugs work to block cell receptors like estrogen and progesterone in breast cancers that are hormone receptor positive. Aromatase inhibitors have been studied in the risk reduction setting. Findings from randomized controlled trials have shown the aromatase inhibitors exemestane and anastrozole may lower the risk of developing breast cancer in postmenopausal women at high risk however aromatase inhibitors are not fda approved for use as risk lowering drugs.

Aromatase inhibitors are used to treat breast cancers in. Pdf version 135kb. Aromatase inhibitors have similar side effects to those of tamoxifen but also affect bone health. Aromatase inhibitors are a class of medicines that work by blocking the enzyme aromatase the enzyme that converts androgens into estrogen.

This means that less estrogen is available to stimulate the growth of estrogen receptor er positive breast cancer cells slowing or inhibiting the. The table below gives you a summary of some of the most common possible side effects of the different hormonal therapy medicines so you can do a general side by side comparison. The pain may be in the hands and wrists. But aromatase inhibitors can cause more heart problems more bone loss osteoporosis and more broken bones than tamoxifen at least for the first few years of treatment.

This side effect can be serious enough to cause some women to stop taking the drugs. Comparison chart of hormonal therapy side effects. Like all drugs aromatase inhibitors can cause side effects but it s not possible to predict how any of the drugs will affect an individual. For more information on any of these side effects visit the treatment side effects section.

Aromatase inhibitors ais like arimidex aromasin and femara are also used to help fight cancer cell regrowth. Some common side effects are described below.